Role of Immunotherapy in Thymic Malignancies Presented By Heather Wakelee at 2019 ASCO Annual Meeting.

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Transcripción de la presentación:

Role of Immunotherapy in Thymic Malignancies Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Disclosures Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Overview Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Slide 4 Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Slide 5 Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Slide 6 Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Autoimmunity in TETs Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Autoimmunity in thymic malignancies Presented By Heather Wakelee at 2019 ASCO Annual Meeting

1st line Case Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Chemotherapy – 1st line Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Anthracycline regimens- RR % Presented By Heather Wakelee at 2019 ASCO Annual Meeting

2nd line Case Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Active Agents in TETs Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Positive “Targeted Drug Trials” Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Other novel combinations Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Rhythmic TET Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Slide 17 Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Some ongoing trials Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Immunotherapy in TC Presented By Heather Wakelee at 2019 ASCO Annual Meeting

PD-L1 score and histology correlation Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Slide 21 Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Avelumab: Phase I (Javelin Solid Tumor) Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Prospective Trial all TETs with Pembrolizumab (200 mg q 3 wks) Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Is it worth the risk? Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Slide 25 Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Pembrolizumab Toxicity Presented By Heather Wakelee at 2019 ASCO Annual Meeting

PD-L1 expression and Pembrolizumab Activity Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Other Biomarkers Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Ongoing IO Clinical Trials in TETs Presented By Heather Wakelee at 2019 ASCO Annual Meeting

Conclusions Presented By Heather Wakelee at 2019 ASCO Annual Meeting