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Differentiation syndrome in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline chemotherapy: characteristics,

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Presentación del tema: "Differentiation syndrome in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline chemotherapy: characteristics,"— Transcripción de la presentación:

1 Differentiation syndrome in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline chemotherapy: characteristics, outcome, and prognostic factors by Pau Montesinos, Juan M. Bergua, Edo Vellenga, Chelo Rayón, Ricardo Parody, Javier de la Serna, Angel León, Jordi Esteve, Gustavo Milone, Guillermo Debén, Concha Rivas, Marcos González, Mar Tormo, Joaquín Díaz-Mediavilla, Jose D. González, Silvia Negri, Elena Amutio, Salut Brunet, Bob Lowenberg, and Miguel A. Sanz Blood Volume 113(4): January 22, 2009 ©2009 by American Society of Hematology

2 Time to occurrence of moderate and severe differentiation syndrome.
Pau Montesinos et al. Blood 2009;113: ©2009 by American Society of Hematology

3 Kaplan-Meier estimates of relapse-free survival depending on development of differentiation syndrome during induction. Kaplan-Meier estimates of relapse-free survival depending on development of differentiation syndrome during induction. (A) In both PETHEMA LPA96 and LPA99 trials; (B) in the PETHEMA LPA 96 trial; (C) in the PETHEMA LPA 99 trial. Pau Montesinos et al. Blood 2009;113: ©2009 by American Society of Hematology


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