5.5 Regulación.

The immune-adrenal axis

5.6 Fisiología del sistema. Renina angiotensina

Angiotensin II (half-life, 1 min). Renina 10 to 20 min

Angiotensin II influences sodium homeostasis changes renal blood flow  maintain a constant glomerular filtration rate. changing the filtration fraction of sodium.  release aldosterone.

5.7 Glucocorticoides.

5.7.1 Acción. 1.  the blood glucose : -antagonizing the secretion and actions of insulin. -  gluconeogenesis. 2.Protein: -mainly catabolic METABOLISM

3.Liver: -stimulate the synthesis of certain enzymes 4.regulate fatty acid mobilization by enhancing the activation of cellular lipase METABOLISM

Leukocytosis. depletion of circulating eosinophils. inhibit the production and action of the mediators of inflammation:lymphokines and prostaglandins. inhibit the production and action of interferon by T lymphocytes and the production of IL-1 and IL-6 by macrophages

inhibit the production of T cell growth factor (IL-2) by T lymphocytes. Reverse macrophage activation and antagonize the action of migration-inhibiting factor (MIF). Reduce prostaglandin and leukotriene production by inhibiting the activity of phospholipase A2. inhibit the production and inflammatory effects of bradykinin, platelet-activating factor, and serotonin

Josef Straka ( )

5.8 Mineralcorticoides.

5.8.1 Efectos en epitelio

5.8.2 Efectos sobre células no epiteliales 1.They do not modify sodium-potassium homeostasis. 2.Aldosterone modifies the expression of several collagen genes and/or genes controlling tissue growth factors. 3. Some effects on nonepithelial cells may be via nongenomic mechanisms. 4.Some of these tissues—the myocardium and vasculature—may also produce aldosterone, although this theory is controversial.

+ +

5.9 Andrógenos.

Baja intensidad   débil de la cortisolemia. > 60% PAM   de la cortisolemia tanto mayor cuanto mayor es la intensidad del trabajo. Mayor  de la cortisolemia cuanto mas depleccionado esté el glucógeno.

Lesión con dolor agudo   de la cortisolemia.  de la cortisolemia tanto en ejercicios estáticos como dinámicos.

6.PANCREAS ENDOCRINO

6.1 Anabolismo y catabolismo de la glucosa.

6.2 Insulina Síntesis. Molécula Insulina.

LANGERHANS, Paul ( )

6.2.2 Secreción.

6.3 Glucagón Síntesis. Molécula Glucagón

6.4 Acciones Insulina y Glucagón.

Ejercicio  a 30’   Insulina. Ejercicio   número de receptores y la sensibilidad a la insulina.

ocrin - ocrin -