Copyright (c) by W. H. Freeman and Company Química Biológica I - Bioquímica I Ácidos Nucleicos Código Genético.

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Copyright (c) by W. H. Freeman and Company Química Biológica I - Bioquímica I Ácidos Nucleicos Código Genético

Copyright (c) by W. H. Freeman and Company Ácidos Nucleicos El DNA contiene la información que determina la secuencia de aminoácidos de las proteínas. Esta información está contenida en unidades llamadas genes. Dogma central : DNA RNA Protein DNA y RNA son polímeros de nucleótidos El RNA forman parte de la maquinaria celular que interviene en la síntesis de proteínas (selección y unión de aa en una secuencia correcta)

Copyright (c) by W. H. Freeman and Company El DNA contiene la información que determina la secuencia de aminoácidos de las proteínas. Esta información está contenida en unidades llamadas genes.

Copyright (c) by W. H. Freeman and Company

DNA y RNA son polímeros de nucleótidos

Copyright (c) by W. H. Freeman and Company Todos los nucleótidos tienen una estructura común

Copyright (c) by W. H. Freeman and Company Bases nitrogenadas en los ácidos nucleicos A, G, T, C están presentes en el DNA A, G, U, C están presentes en el RNA

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Terminología nucleósidos/ nucleótidos

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Unión entre nucleótidos

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El DNA es una doble hélice de cadenas complementarias antiparalelas Hydrogen bonding between complementary base pairs (A-T or G-C) holds the two strands together

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RNA molecules exhibit varied conformations

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Propiedades químicas de los ácidos nucleicos

Copyright (c) by W. H. Freeman and Company Hidrólisis en medio alcalino Hidrólisis en medio ácido

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Desnaturalización del DNA

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Nucleic acid synthesis Both DNA and RNA chains are produced by copying of template DNA strands Nucleic acid strands grow in the 5 3 direction RNA polymerases can initiate strand growth but DNA polymerases require a primer strand

Copyright (c) by W. H. Freeman and Company Several common principles apply to the synthesis of proteins and nucleic acids Proteins and nucleic acids are made up of a limited number of different monomeric building blocks The monomers are added one at a time Each polypeptide and polynucleotide chain has a specific starting point, and growth proceeds in one direction to a fixed terminus The primary synthetic product is often modified

Copyright (c) by W. H. Freeman and Company

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