Enhancing Checkpoint Inhibitors in Triple-Negative Breast Cancer Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting.

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Transcripción de la presentación:

Enhancing Checkpoint Inhibitors in Triple-Negative Breast Cancer Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Disclosures Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Low Response Rates with Chemotherapy in Metastatic TNBC Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

TIL Expression as a Prognostic Marker Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Variability in Response to Single Agent Checkpoint Inhibitors Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Response Associates with Improved OS to Checkpoint Inhibitors Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Combination Strategies to Enhance Immunogenicity? Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Olympiad Trial: Parp Inhibitors Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Rationale for Parp + Checkpoint Inhibitors Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Open-label, multi-tumor, Phase II basket study of olaparib and durvalumab (MEDIOLA): Germline BRCA-mutated HER2- MBC Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

MEDIOLA: Olaparib + Durvalumab (n=25) Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

TOPACIO: Niraparib + Pembrolizumab (n=46) Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Rationale for Chemotherapy or XRT + Checkpoint Inhibitor Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Concomitant Chemotherapy + Checkpoint Inhibitor Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Operable Setting: Pathologic Response in ISPY2 Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

TONIC Trial: Induction Tx + Nivolumab (n=66) Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

TOPACIO and TONIC Trials Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Future Directions? Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Parp inhibitor + Checkpoint Inhibitor Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Chemotherapy + Checkpoint Inhibitor Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Trials in the Operable Setting Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Potential Targets in Cancer-Immunity Cycle Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

Summary Presented By Kevin Kalinsky at 2018 ASCO Annual Meeting

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