IV WORKSHOP RADIACIÓN NATURAL Y MEDIO AMBIENTE Epidemiología y radón: últimos avances. XM Barros Dios Prof. Titular de Medicina Preventiva e Saúde Pública.

Presentación del tema: "IV WORKSHOP RADIACIÓN NATURAL Y MEDIO AMBIENTE Epidemiología y radón: últimos avances. XM Barros Dios Prof. Titular de Medicina Preventiva e Saúde Pública."— Transcripción de la presentación:

1 IV WORKSHOP RADIACIÓN NATURAL Y MEDIO AMBIENTE Epidemiología y radón: últimos avances. XM Barros Dios Prof. Titular de Medicina Preventiva e Saúde Pública Universidade de Santiago de Compostela

2 Epidemiología y radón: últimos avances 1. Robertson LB. Stevenson DS. Conen F. Test of a northwards-decreasing Rn-222 source termby comparison of modelled and observed atmospheric Rn-222 concentrations. [Article] TellusSeries B-Chemical & Physical Meteorology. 57(2):116-123, 2005 Apr. 2. Zahorowski W. Chambers S. Wang T. Kang CH. Uno I. Poon S. Oh SN. Werczynski S. KimJ. Henderson-Sellers A. Radon-222 in boundary layer and free tropospheric continental outflowevents at three ACE-Asia sites. [Article] Tellus Series B-Chemical & Physical Meteorology.57(2):124-140, 2005 Apr. 3. Sasaki T. Gunji Y. Okuda T. Theoretical study of high radon emanation. [Article] Journal ofNuclear Science & Technology. 42(2):242- 249, 2005 Feb. 4. Oufni L. Misdaq MA. Radon emanation and uranium content in an endokarstic formationusing solid state nuclear track detectors. [Article] Journal de Physique IV. 123:377-380, 2005Mar. 5. Bochicchio F. Forastiere F. Farchi S. Quarto M. Axelson O. Residential radon exposure, dietand lung cancer: A case-control study in a Mediterranean region. [Article] International Journalof Cancer. 114(6):983-991, 2005 May 10. 10. Pearce J. Boyle P. Examining the relationship between lung cancer and radon in small areas across Scotland. [Article] Health & Place. 11(3):275-282, 2005 Sep. 18. Song G. Zhang BY. Wang XM. Gong JP. Chan D. Bernett J. Lee SC. Indoor radon levels inselected hot spring hotels in Guangdong, China. [Article] Science of the Total Environment.339(1-3):63-70, 2005 Mar 1. 19. Gulson BL. Mizon KJ. Dickson BL. Korsch MJ. The effect of exposure to employees frommining and milling operations in a uranium mine on lead isotopes - a pilot study. [Article]Science of the Total Environment. 339(1-3):267-272, 2005 Mar 1. 20. Singh S. Kumar M. Mahajan RK. The study of indoor radon in dwellings of Bathindadistrict, Punjab, India and its correlation with uranium and radon exhalation rate in soil.[Article] Radiation Measurements. 39(5):535-542, 2005 Oct. 27. Mohamed A. Activity size distributions of some naturally occurring radionuclides Be-7, K-40 and Pb-212 in indoor and outdoor environments. [Article] Applied Radiation & Isotopes.62(5):751-757, 2005 May. 28. Kullab M. Assessment of radon-222 concentrations in buildings, building materials, waterand soil in Jordan. [Article] Applied Radiation & Isotopes. 62(5):765-773, 2005 May. 31. Chen J. Estimated risks of radon-induced lung cancer for different exposure profiles basedon the new EPA model. [Article] Health Physics. 88(4):323-333, 2005 Apr. 32. Gaul WC. Underhill DW. Dynamic adsorption of radon by activated carbon. [Article]Health Physics. 88(4):371-378, 2005 Apr.

3 Epidemiología y radón: últimos avances 33. Gokmen A. Gokmen IG. Hung YT. Radon pollution control. [Article] ADVANCED AIR AND NOISE POLLUTION CONTROL. 2 PG. 335-357. 2005. 43. Villalba L. Sujo LC. Cabrera MEM. Jimenez AC. Villalobos MR. Mendoza CJD. Tenorio LAJ. Rangel ID. Peraza EFH. Radon concentrations in ground and drinking water in the state ofChihuahua, Mexico. [Article] Journal of Environmental Radioactivity. 80(2):139- 151, 2005. 44. Jang M. Kang CS. Moon JH. Estimation of Rn-222 release from the phosphogypsum boardused in housing panels. [Article] Journal of Environmental Radioactivity. 80(2):153-160, 2005. 45. Lario J. Sanchez-Moral S. Canaveras JC. Cuezva S. Soler V. Radon continuous monitoringin Altamira Cave (northern Spain) to assess user's annual effective dose. [Article] Journal ofEnvironmental Radioactivity. 80(2):161-174, 2005. 46. Johnston PN. Hult M. Gasparro J. Martinez-Canet MJ. Vasselli R. McKenzie RJ. SolomonSB. Lambrichts I. The distribution of Pb-210 in human bone and its impact on methods for the retrospective estimation of Rn-222 exposure from in vivo measurements. [Article] Journal ofEnvironmental Radioactivity. 80(2):245-257, 2005. 52. Fournier F. Groetz JE. Jacob F. Crolet JM. Lettner H. Simulation of radon transport throughbuilding materials: Influence of the water content on radon exhalation rate. [Article] Transportin Porous Media. 59(2):197-214, 2005 May. 53. Misdaq MA. Amghar A. Radon and thoron emanation from various marble materials: impacton the workers. [Article] Radiation Measurements. 39(4):421-430, 2005 Aug. 54. Sharaf MA. Abo-Elmagd M. Thermal effects on CR-39 detector response and permeabilityof some membranes used in radon measurements. [Article] Radiation Measurements.39(4):441-445, 2005 Aug. 56. Dulaiova H. Peterson R. Burnett WC. Lane-Smith D. A multi-detector continuous monitorfor assessment of Rn-222 in the coastal ocean. [Article] Journal of Radioanalytical & NuclearChemistry. 263(2):361-365, 2005 Jan. 57. Petford N. Wertheim D. Miller JA. Radon track imaging in CR-39 plastic detectors usingconfocal scanning laser microscopy. [Article] Journal of Microscopy. 217(3):179-183, 2005Mar. 58. Laquatra J. Maxwell LE. Pierce M. Indoor air pollutants: Limited-resource households andchild care facilities. [Article] Journal of Environmental Health. 67(7):39-43, 2005 Mar. 61. Radon and lung cancer risk. [News Item] European Journal of Cancer. 41(3):338, 2005Feb.

4 Epidemiología y radón: últimos avances 65. Hartmann J. Levy JK. Hydrogeological and gasgeochemical earthquake precursors - Areview for application [Review]. [Review] Natural Hazards. 34(3):279-304, 2005 Mar. 67. Poncela LSQ. Navarro PLF. Fernandez CS. Matarranz JLM. Garcia JA. Natural radiationexposure in the Campo Aranuelo region in the surroundings of Almaraz nuclear power station (Spain). [Article] Journal of Environmental Radioactivity. 79(3):347-354, 2005. 68. El-Hussein A. A study on natural radiation exposure in different realistic living rooms.[Article] Journal of Environmental Radioactivity. 79(3):355-367, 2005. 69. Porsani JL. Elis VR. Hiodo FY. Geophysical investigations for the characterization offractured rock aquifers in Itu, SE Brazil. [Article] Journal of Applied Geophysics. 57(2):119-128, 2005 Feb. 71. Krewski D. Lubin JH. Zielinski JM. Alavanja M. Catalan VS. Field RW. Klotz JB.Letourneau EG. Lynch CF. Lyon JI. Sandler DP. Schoenberg JB. Steck DJ. Stolwijk JA.Weinberg C. Wilcox HB. Residential radon and risk of lung cancer - A combined analysis of 7 north American case-control studies. [Article] Epidemiology. 16(2):137-145, 2005 Mar. 72. Curzio G. Mazed D. Ciolini R. Del Gratta A. Gentili A. Effect of air on gas amplificationcharacteristics in argon-propane (1%)-based proportional counters for airborne radon monitoring. [Article] Nuclear Instruments & Methods in Physics Research Section A-Accelerators Spectrometers Detectors & Associated Equipment. 537(3):672-682, 2005 Feb 1. 73. Auvinen A. Salonen L. Pekkanen J. Pukkala E. Ilus T. Kurttio P. Radon and other naturalradionuclides in drinking water and risk of stomach cancer: A case-cohort study in Finland. [Article] International Journal of Cancer. 114(1):109-113, 2005 Mar 10. 76. Darby S. Hill D. Auvinen A. Barrios-Dios JM. Baysson H. Bochicchio F. Deo H. Falk R.Forastiere F. Hakama M. Heid I. Kreienbrock L. Kreuzer M. Lagarde F. Makelainen I. Muirhead C. Oberaigner W. Pershagen G. Ruano-Ravina A. Ruosteenoja E. Rosario AS. Tirmarche M. Tomasek L. Whitley E. Wichmann HE. et al. Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies. [Article] British Medical Journal. 330(7485):223-226, 2005 Jan 29. 77. Watts G. Science commentary: Radon blues. [Editorial Material] British Medical Journal. 330(7485):226-227, 2005 Jan 29. 78. Katona T. Kanyar B. Somlai J. Cost assessment of ventilation and averted dose due to radon in dwellings. [Article] Journal of Environmental Radioactivity. 79(2):223-230, 2005. 83. Denman AR. Phillips PS. Tornberg R. Groves-Kirkby C. Analysis of the individual health benefits accruing from a domestic radon remediation programme. [Article] Journal of Environmental Radioactivity. 79(1):7-23, 2005.

5 Epidemiología y radón: últimos avances 84. Paridaens J. de Saint-Georges L. Vanmarcke H. Mitigation of a radon-rich Belgian dwelling using active subslab depressurization. [Article] Journal of Environmental Radioactivity. 79(1):25-37, 2005. 85. Ramola RC. Negi MS. Choubey VM. Radon and thoron monitoring, in the environment of Kumaun Himalayas: survey and outcomes. [Article] Journal of Environmental Radioactivity. 79(1):85-92, 2005. 88. Coskeran T. Denman A. Phillips P. Tornberg R. A cost-effectiveness analysis of domestic radon remediation in four primary care trusts located in Northamptonshire, UK. [Article] Health Policy. 71(1):43-56, 2005 Jan. 90. de Jong P. van Dijk W. de Vries W. van der Graaf ER. Roelofs LMM. Interlaboratory comparison of three methods for the determination of the radon exhalation rate of building materials. [Article] Health Physics. 88(1):59-64, 2005 Jan. 91. Wichmann HE. Rosario AS. Heid IM. Kreuzer M. Heinrich J. Kreienbrock L. Increased lung cancer risk due to residential radon in a pooled and extended analysis of studies in Germany. [Article] Health Physics. 88(1):71-79, 2005 Jan. 92. Lu XW. Radioactive analysis of cement and its products collected from Shaanxi, China. [Article] Health Physics. 88(1):84-86, 2005 Jan. 93. Hanamoto K. Yamaoka K. A comparative study on radioactive characteristics of the minerals for radon therapy. [Article] Radiation Measurements. 39(2):157-160, 2005 Feb. 94. Chen DY. You XB. Hu RY. Indoor radon survey in indoor environments in Zhuhai city, China. [Article] Radiation Measurements. 39(2):205-207, 2005 Feb. 95. Baykara O. Dogru M. Inceoz M. Aksoy E. Measurements of radon emanation from soil samples in triple-junction of North and East Anatolian active faults systems in Turkey. [Article] Radiation Measurements. 39(2):209-212, 2005 Feb. 96. Singh K. Singh M. Singh S. Sahota HS. Papp Z. Variation of radon (Rn-222) progeny concentrations in outdoor air as a function of time, temperature and relative humidity. [Article] Radiation Measurements. 39(2):213-217, 2005 Feb. 97. Garcia-Vindas JR. Monnin MM. Radon concentration measurements in the presence of water and its consequences for Earth sciences studies. [Article] Radiation Measurements. 39(3):319-322, 2005 Jun. 98. Abumurad KM. Al-Tamimi MH. Natural radioactivity due to radon in Soum region, Jordan. [Article] Radiation Measurements. 39(1):77- 80, 2005 Jan.

6 Epidemiología y radón: últimos avances 99. Singh S. Kumar A. Singh B. Passive integrating radon studies for environmental monitoring in Hamirpur district, Himachal Pradesh, India using solid state nuclear track detectors. [Article] Radiation Measurements. 39(1):81-85, 2005 Jan. 100. Poncela LSQ. Fernandez PL. Arozamena JG. Fernandez CS. A method for measuring effective radon diffusion coefficients in radon barriers by using modified Lucas cells. [Article] Radiation Measurements. 39(1):87-89, 2005 Jan. 101. Nevinsky I. Tsvetkova T. SSNTDs in the automatic detector of radon. [Article] Radiation Measurements. 39(1):115- 119, 2005 Jan. 102. Gillmore G. Gilbertson D. Grattan J. Hunt C. McLaren S. Pyatt B. Banda RM. Barker G. Denman A. Phillips P. Reynolds T. The potential risk from (222)radon posed to archaeologists and earth scientists: reconnaissance study of radon concentrations, excavations, and archaeological shelters in the Great Cave of Niah, Sarawak, Malaysia. [Article] Ecotoxicology & Environmental Safety. 60(2):213-227, 2005 Feb. 103. Swakon J. Kozak K. Paszkowski M. Gradzinski R. Loskiewicz J. Mazur J. Janik M. Bogacz J. Horwacik T. Olko P. Radon concentration in soil gas around local disjunctive tectonic zones in the Krakow area. [Article] Journal of Environmental Radioactivity. 78(2):137-149, 2005. 104. Richon P. Perrier F. Sabroux JC. Trique M. Ferry C. Voisin V. Pili E. Spatial and time variations of radon-222 concentration in the atmospheres of a dead-end horizontal tunnel. [Article] Journal of Environmental Radioactivity. 78(2):179-198, 2005. 105. Yu KN. Nikezic D. Comment on "radon-222 signatures of natural ventilation regimes in an un derground quarry [Journal of Environmental Radioactivity 71 (2004) 17-32; 72(2004)369-370]. [Letter] Journal of Environmental Radioactivity. 78(2):247-248, 2005. 106. Iimoto T. Tokonami S. Morishita Y. Kosako T. Application of activated charcoal radon collectors in high humidity environments. [Article] Journal of Environmental Radioactivity. 78(1):69-76, 2005. 107. Srivastava A. An overview of an indoor radon study carried out in dwellings in India and Bangladesh during the last decade using solid state nuclear track detectors. [Article] Journal of Environmental Radioactivity. 78(1):113-121, 2005.

7 Epidemiología y radón: últimos avances British Medical Journal 2005:Estudio colaborativo de 13 investigaciones europeas (pooling study) Epidemiology 2005: Analisis combinado de 7 estudios de C-C norteamericanos Health Physics 2005:Pooling estudio de dos casos-controles en Alemania Int J Cancer 2005:Estudio C_C sobre cáncer de pulmón, radón domiciliario, y dieta en una región mediterránea.

8 Epidemiología y radón: últimos avances ESTUDIO EUROPEO (13 CASOS-CONTROLES) Br Med J 2005;330:223-26. BMJ, doi:10.1136/bmj.38308.477650.63 (published 21 December 2004)

9 Epidemiología y radón: últimos avances

10 Br Med J 2005 7.148 casos de cáncer pulmonar de 13 países europeos 14.208 controles Media de años de exposición al Rn residencial: 5.34 años Niveles medios de Rn: Casos: 104 Bq/m 3 Controles: 97 Bq/m 3 Nivel de incremento del riesgo en sujetos con medidas de radón directas: 8,4% [3,0 – 15,8] por cada 100 Bq/m 3 Nivel de incremento del riesgo en sujetos con exposición ajustadando el error aleatorio de las medidas: 16% [5 – 31] Riesgo absoluto a 75 años a exposiciones de 0, 100 y 400 Bq: No fumadores: 0,4%0,5%0,7% Fumadores : 10%12%16%

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18 British Medical Journal 2005:Estudio colaborativo de 13 investigaciones europeas (pooling study) Epidemiology 2005: Análisis combinado de 7 estudios de C-C norteamericanos Health Physics 2005:Pooling estudio de dos casos-controles en Alemania Int J Cancer 2005:Estudio C_C sobre cáncer de pulmón, radón domiciliario, y dieta en una región mediterránea.

19 Epidemiología y radón: últimos avances ESTUDIO NORTEAMERICANO (Siete Casos-Controles) Epidemiology 2005; 16 (2):137-145

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21 Epidemiology 2005 Siete estudios de casos y controles realizados en Norteamérica. 3.662 casos de cáncer pulmonar 4.966 controles Exposición de 5 a 30 años Incremento del riesgo por cada 100 Bq de 1,1% (similar al 1,12% estimado en los estudios de mineros)

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27 British Medical Journal 2005:Estudio colaborativo de 13 investigaciones europeas (pooling study) Epidemiology 2005: Analisis combinado de 7 estudios de C-C norteamericanos Health Physics 2005:Pooling estudio de dos casos-controles en Alemania Int J Cancer 2005:Estudio C_C sobre cáncer de pulmón, radón domiciliario, y dieta en una región mediterránea.

28 Epidemiología y radón: últimos avances

29 Health Physics 2005 Dos estudios de casos y controles realizados en Alemania entre 1990 y 1997. 2.963 casos de cáncer pulmonar. 4.232 controles Exposición de 5 a 35 años. Concentración media de Rn: 61 Bq/m 3 Ajustados por tabaco y exposición a asbesto, los riesgos resultan ser, con referencia a la exposición a menos de 50 Bq, de: OR=0,97 de 50 a 80 Bq OR=1,06 de 80 a 140 Bq OR=1,40 para más de 140 Bq El incremento, lineal, por cada 100 Bq fue de 0,10[-0,02-0,30] Y en los de menor movilidad residencial de 0,14 [-0,03 –0,55]

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36 British Medical Journal 2005:Estudio colaborativo de 13 investigaciones europeas (pooling study) Epidemiology 2005: Analisis combinado de 7 estudios de C-C norteamericanos Health Physics 2005:Pooling estudio de dos casos-controles en Alemania Int J Cancer 2005:Estudio C_C sobre cáncer de pulmón, radón domiciliario, y dieta en una región mediterránea (Italia)

37 Epidemiología y radón: últimos avances

38 Int J Cancer 2005 Estudio italiano incluyendo dieta como factor de riesgo de CP. 384 casos de CP 404 controles Exposición residencial a Rn de 5 a 30 años. ORs: 1,30 [1,03 – 1,64] para 50-99 Bq 1,48 [1,08 – 2,02] para 100-199 Bq 1,49 [0,82 – 2,71] para 200-399 Bq 2,89 [0,45 – 18,6] para >400 Bq El exceso de riesgo por cada 100 Bq/m 3 se situó en: 0,14 [-0,11=0,46] para todos los sujetos 0,24 [-0,09=0,70] para las medidas completas 0,30 [-0,08=0,82] para aquellos de menor movilidad (1-2 casas)

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43 Darby S, Hill D, Deo H, Auvinen A, Barros-Dios JM, Baysson H, et al. Residential radon and lung cancer: detailed results of a collaborative analysis of individual data on 7,148 subjects with lung cancer and 14, 208 subjects without lung cancer from 13 epidemiological studies in Europe. Scand J Work Environ Health (in press).