THE CELL THEORY © 2016 Paul Billiet ODWSODWS. What level of complexity is necessary for life? Aristotle (384 – 322BC) Matter Organised material (living)

Presentación del tema: "THE CELL THEORY © 2016 Paul Billiet ODWSODWS. What level of complexity is necessary for life? Aristotle (384 – 322BC) Matter Organised material (living)"— Transcripción de la presentación:

1 THE CELL THEORY © 2016 Paul Billiet ODWSODWS

2 What level of complexity is necessary for life? Aristotle (384 – 322BC) Matter Organised material (living) Unorganised material (non-living) Heterogeneous (organs) Homogeneous (tissues) © 2016 Paul Billiet ODWSODWS

3 Tissues and Organs Muscle tissue (surloin steak) Kidney longitudinal section © 2016 Paul Billiet ODWSODWS

4 What level of complexity is necessary for life? C17th microscopists discovered tissues were made of cells (Hooke 1665 and Leeuwenhoek 1677) Cork cells © 2016 Paul Billiet ODWSODWS

5 Cells C18th and C19th showed that tissues were made of cells. The cells of a particular tissue have a common structure. Liver cells © 2016 Paul Billiet ODWSODWS

6 What is a cell? Taken to its simplest form A plasma membrane… surrounding cytoplasm… containing hereditary material. © 2016 Paul Billiet ODWSODWS

7 Unicellular organisms Some organisms only consist of a single cell yet carry out all life functions But these do usually have the components of cells (nucleus, membrane etc) Paramecium © 2016 Paul Billiet ODWSODWS

8 What are life functions? Nutrition Metabolism Growth Response Excretion Homeostasis Reproduction. © 2016 Paul Billiet ODWSODWS

9 Multicellular organisms Development of a chick embryo © 2016 Paul Billiet ODWSODWS

10 What level of complexity is necessary for life? Xavier Bichat (1771- 1802): An organ is composed of different tissues Several organs can be grouped together as an organ-system (e.g. the digestive system) An idea of hierarchy of structure developed into: Organism Organ-system Organ Tissue Cell © 2016 Paul Billiet ODWSODWS

11 What level of complexity is necessary for life? Purkinje (1835) Observed a fertilised hen's egg (a single cell) could develop into an embryo (many specialised cells in a compact mass) C19th botanists showed that plant tissues consist of many different types of cells So all living organisms seem to be composed of cells © 2016 Paul Billiet ODWSODWS

12 THE CELL THEORY Matthias Schleiden (1838) & Theodor Schwann (1839) “The cell is the basic unit of living tissue” The cell is an autonomous unit (“a citizen”) grouped together to form an organism (“the society”). © 2016 Paul Billiet ODWSODWS

13 « Omnis cellula e cellula » Remak & Virchow (1858) noted that: “ all cells come from pre-existing cells” Cell division © 2016 Paul Billiet ODWSODWS

14 Is the cell really that autonomous? Cells in multicellular organisms © 2016 Paul Billiet ODWSODWS

15 Cellular components Some cells lack the basic components But as a result their functions are affected. Red blood cells © 2016 Paul Billiet ODWSODWS

16 Plasmodesmata Strasberger observed: Cells are connected in an organism sometimes by cytoplasmic bridges. Not all cells seem to be completely contained in a plasma membrane. Black sapote (Diospyros) fruit © 2016 Paul Billiet ODWSODWS

17 Acellular organisms Some organisms do not have cellular compartments Common field mushroom (Agaricus bisporus) Fungal hyphae © 2016 Paul Billiet ODWSODWS

18 Giant algal cells http://www.coexploration.org/bbsr/coral/assets/images/acetabularia.jpg Acetabularia © 2016 Paul Billiet ODWSODWS

19 Acellular tissues: Striated muscle fibres Striated muscle viewed at x400 © 2016 Paul Billiet ODWSODWS

20 Homeostasis Sherrington and Pavlov neurophysiologists: Cells communicate with one another They are co-ordinated in their actions Spiney dendrites of the hippocampus region of the brain. Red dots show the spines associated with synapses. © 2016 Paul Billiet ODWSODWS

21 Tissue culture Cells can be cultured away from a body But this often requires elaborate support systems Tissue culture hood U of Wisconsin © 2016 Paul Billiet ODWSODWS

22 THE ORGANISMAL THEORY The counter arguments: Reichert a morphologist: Argued that a multicellular organism has a structured plan Frog embryo Frog embryo fate map © 2016 Paul Billiet ODWSODWS

23 SUMMARY 2. Certain cells lack the basic components e.g. red blood cells Cells in multicellular organisms are highly specialised Unicellular organisms have a cytoplasm that is not subdivided Should they be considered as acellular? 2. The basic components of the cell are repeated in every cell Where they are absent or in multiples this affects life processes e.g. anucleate red blood cells cannot reproduce e.g. muscles cells contain many nuclei but form from many cells that fuse 1. Some organisms are not divided into cellular compartments = non-cellular 1. Multicellular organisms develop from a single fertilised germ cell (the zygote) THE ORGANISMAL THEORY THE CELL THEORY © 2016 Paul Billiet ODWSODWS

24 SUMMARY 4. Homeostatic control and co- ordination is required to maintain the whole organism whether it is unicellular or multicellular. 3. Remove cells from complete multicellular organisms requires elaborate life support systems to keep them alive 3. All cells come from cells Cells can be taken from organisms and cultured away from the body New individuals can be cultured from isolated cells THE ORGANISMAL THEORY THE CELL THEORY © 2016 Paul Billiet ODWSODWS

25 Cell theory or organismal theory? That the cell is the basic unit of living organisms is accepted That unicellular organisms carry out all the functions of life is accepted BUT multicellular organisms are not simply a mass of similar independent building blocks. © 2016 Paul Billiet ODWSODWS

26 More is different! As a multicellular organism grows and develops it follows a structured plan The cells specialise ( differentiate ) The whole organism shows homeostatic control A developing multicellular organism shows emergent properties It is not just the sum of the parts. © 2016 Paul Billiet ODWSODWS