Cervarix René Quiroz Morales José Alfredo Zaragoza Aguilar

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Transcripción de la presentación:

Cervarix René Quiroz Morales José Alfredo Zaragoza Aguilar Luis Sánchez Pérez Irving Utrera Espindola Alan Rodríguez Enríquez

Virus del papiloma humano (VPH) Al menos una docena de tipos de VPH pueden provocar cáncer, pero dos en particular (16 y 18) son los causantes del 70% de estos padecimientos. Aprobado por la FDA en 2009.

Fabricación Estructura viral del VPH

Producción de proteína recombinante

Choque osmótico Cromatografía Filtración nanometrica Ultrafiltración Filtración estéril

Diagrama general

Mecanismo de acción

Adyuvante

Casos clínicos.

Venta

Referencias [1] Human Papillomavirus (HPV) Infection. CDC. Obtenida el: 25/06/17. [En línea]. https://www.cdc.gov/std/tg2015/hpv.htm [2] FDA Licensure of Bivalent Human Papillomavirus Vaccine (HPV2, Cervarix) for Use in Females and Updated HPV Vaccination Recommendations from the Advisory Committee on Immunization Practices (ACIP). CDC. MMWR. 2010/59 (20); 626-629. [3] Christopher B. Buck, Patricia M. Day, Benes L. Trus, The papillomavirus major capsid protein L1, Virology, Volume 445, Issue 1, 2013, Pages 169-174, ISSN 0042-6822, http://dx.doi.org/10.1016/j.virol.2013.05.038.(http://www.sciencedirect.com/science/article/pii/S0042 682213003322) [4] Scheffer, K.D., Gawlitza, A., Spoden, G.A., Zhang, X.A., Lambert, C., Berditchevski, F., Florin, L., 2013. Tetraspanin CD151 mediatespapillomavirustype 16 endocytosis. J. Virol. 87, 3435–3446.