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High levels of anti-tuberculin (IgG) antibodies correlate with the blocking of T-cell proliferation in individuals with high exposure to Mycobacterium.

Publicada porGerald Atkinson Modificado hace 6 años

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Presentación del tema: "High levels of anti-tuberculin (IgG) antibodies correlate with the blocking of T-cell proliferation in individuals with high exposure to Mycobacterium."— Transcripción de la presentación:

1 High levels of anti-tuberculin (IgG) antibodies correlate with the blocking of T-cell proliferation in individuals with high exposure to Mycobacterium tuberculosis  Edmond J. Feris, Liliana Encinales, Carlos Awad, Joel N.H. Stern, Inna Tabansky, Luis Jiménez-Alvarez, Gustavo Ramírez-Martínez, Alfredo Cruz-Lagunas, Karen Bobadilla, Eduardo Márquez, Julio Granados-Montiel, Tatiana S. Rodriguez-Reyna, Marcelo Fernandez- Vina, Julio Granados, Joaquin Zuñiga, Edmond J. Yunis  International Journal of Infectious Diseases  Volume 43, Pages (February 2016) DOI: /j.ijid Copyright © 2015 The Authors Terms and Conditions

2 Figure 1 T-cell proliferation induced by tuberculin or Candida antigens in the different TB risk groups. Bar graph depicting the stimulation index (proliferation) levels of T-cells for individuals from each of the groups in the presence of human AB or autologous serum: high-risk (HR), intermediate risk (group A), and low risk (group B). Treatment with autologous serum (with high levels of anti-tuberculin IgG antibodies, black solid bars) provokes the blocking of T-cell proliferation responses after stimulation with tuberculin (Bar graph A), but not with Candida antigen stimulation (Bar graph B). Only one subject from group B and two from group A exhibited blocking activity in the presence of autologous serum. International Journal of Infectious Diseases  , 21-24DOI: ( /j.ijid ) Copyright © 2015 The Authors Terms and Conditions

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