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Phase I clinical trial in healthy adults of a nasal vaccine candidate containing recombinant hepatitis B surface and core antigens  Arístides Aguilar.

Publicada porInmaculada Coronel Navarrete Modificado hace 6 años

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Presentación del tema: "Phase I clinical trial in healthy adults of a nasal vaccine candidate containing recombinant hepatitis B surface and core antigens  Arístides Aguilar."— Transcripción de la presentación:

1 Phase I clinical trial in healthy adults of a nasal vaccine candidate containing recombinant hepatitis B surface and core antigens  Arístides Aguilar Betancourt, C.A. González Delgado, Z. Cinza Estévez, J. Cabrera Martínez, G. Véliz Ríos, S.R. Moreno Aureoles- Roselló, R. Alemán Zaldívar, M. Alonso Guzmán, N. Figueroa Baile, P.A. Días Reyes, L. Olivera Ruano, A. Correa Fernández, Y. Lobaina-Matos, A. Delahanty Fernández, A.I. Juvier Madrazo, M.I. Alonso Martínez, M. Lago Baños, N. Puble Alvarez, M. David Baldo, R.E. Soto Mestre, M.V. Pérez Pérez, M.E. Peña Martínez, D. Acosta Escobar, M.J. Cerna Guanche, L. Mila Cáceres, R. Sánchez Betancourt, E. Hardy Rando, G.E. Guillén Nieto, V.L. Muzio González, J.C. Aguilar Rubido  International Journal of Infectious Diseases  Volume 11, Issue 5, Pages (September 2007) DOI: /j.ijid Copyright © 2006 International Society for Infectious Diseases Terms and Conditions

2 Figure 1 Kinetics of the anti-HBsAg antibody response in healthy adults nasally immunized with HBcAg–HBsAg vaccine candidate. Vaccine schedule: 0, 7, 15, 30, and 60 days. Blood samples were collected from subjects at days 30, 60, and 90. Vertical arrows: nasal vaccine inoculations. International Journal of Infectious Diseases  , DOI: ( /j.ijid ) Copyright © 2006 International Society for Infectious Diseases Terms and Conditions

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