Autologous Stem Cell Transplantation for Follicular Lymphoma: Favorable Long-Term Survival Irrespective of Pretransplantation Rituximab Exposure Ana.

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Transcripción de la presentación:

Autologous Stem Cell Transplantation for Follicular Lymphoma: Favorable Long-Term Survival Irrespective of Pretransplantation Rituximab Exposure Ana Jiménez-Ubieto, Carlos Grande, Dolores Caballero, Lucrecia Yáñez, Silvana Novelli, Miguel Teodoro Hernández-Garcia, María Manzanares, Reyes Arranz, José Javier Ferreiro, Sabella Bobillo, Santiago Mercadal, Andrea Galeo, Javier López Jiménez, José María Moraleda, Carlos Vallejo, Carmen Albo, Elena Pérez, Carmen Marrero, Laura Magnano, Luis Palomera, Isidro Jarque, Pilar Martínez- Sánchez, Alejandro Martín, Erika Coria, Armando López-Guillermo, Antonio Salar, Juan José Lahuerta Biology of Blood and Marrow Transplantation Volume 23, Issue 10, Pages 1631-1640 (October 2017) DOI: 10.1016/j.bbmt.2017.05.021 Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Outcomes in the overall patient population according to the decade of transplantation: 1989-1999 versus 2000-2007. Shown are Kaplan–Meier curves of PFS (A) and OS (B) from the time of HDT/ASCT. Biology of Blood and Marrow Transplantation 2017 23, 1631-1640DOI: (10.1016/j.bbmt.2017.05.021) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Outcomes in patients according to disease status at transplantation. Shown are Kaplan–Meier curves of PFS (A) and OS (B) from the time of HDT/ASCT according to disease status at the time of HDT/ASCT. PD, refractory disease. Biology of Blood and Marrow Transplantation 2017 23, 1631-1640DOI: (10.1016/j.bbmt.2017.05.021) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Outcomes in patients according to exposure to rituximab before transplantation. Shown are Kaplan–Meier curves of PFS (A) and OS (B) according to whether patients received rituximab as part of therapy before HDT/ASCT. Biology of Blood and Marrow Transplantation 2017 23, 1631-1640DOI: (10.1016/j.bbmt.2017.05.021) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 Outcomes in patients who underwent transplantation in CR according to exposure to rituximab before transplantation. Shown are Kaplan–Meier curves of PFS (A) and OS (B) according to whether patients received rituximab as part of therapy before HDT/ASCT and disease status (CR1 versus CR2/3) at the time of HDT/ASCT. R+, patients who had received rituximab before HDT/ASCT. R-, patients who had not received rituximab before HDT/ASCT. Biology of Blood and Marrow Transplantation 2017 23, 1631-1640DOI: (10.1016/j.bbmt.2017.05.021) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions